KI

EXTERNALL REGULATION OF CAR T-CELL ACTIVITY FOR A SAFER AND EFFECTIVE CANCER

Chimeric antigen receptor T cells (CAR T) cancer therapies are advanced and high-value therapies that enhance the immune response against tumor cells. Tumor specificity is achieved by genetically modifying T-cells. As of 2019, two of such therapies were available in the US and some EU markets, both targeting the CD19 antigen. The latter is expressed in cancers such as diffuse large B-cell lymphoma. The development of new CAR T-cell therapies is going towards new antigen targets and limiting the adverse…

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Okrogla Miza: Vloga znanosti in inovacij pri prilagajanju na podnebne spremembe

Okrogla miza Vloga znanosti in inovacij pri prilagajanju na podnebne spremembe je bila organizirana v sodelovanju z gibanjem Mladi za podnebno pravičnost, ki so dogodek tudi povezovali.   Več informacij najdete na spletni strani Kemijskega inštituta ter na Facebook strani, kjer si lahko ogledate video posnetek: https://www.ki.si/novice/single-prikaz/novice/novica/omizje-vloga-znanosti-in-inovacij-pri-prilagajanju-na-podnebne-spremembe/?tx_ttnews%5BcalendarMonth%5D=6&tx_ttnews%5BcalendarYear%5D=2020&cHash=d2d25f78f14509380c20d1e1d82ca376 https://www.facebook.com/watch/live/?v=2287824978193947&ref=watch_permalink

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ONE-STEP SYNTHESIS OF GLYCIDOL FROM GLYCEROL IN GAS-PHASE FIXED-BED CONTINOUS FLOW REACTOR OVER ALKALI METAL PROMOTED ALUMINOSILICATE ZEOLITE CATALYST

The present invention relates to the use of alkali metal promoted aluminosilicate zeolite catalyst for the direct gas-phase conversion of glycerol to glycidol, as well as to a process for the production of glycidol from glycerol in a fixed-bed continuous flow reactor in the presence of such a heterogeneous catalyst. The method comprises conversion of glycerol to glycidol in the range of temperature 250-450 °C, glycerol concentration 1-60 wt%, total gas hourly space velocity 100-2500 h-1, weight of catalyst 0.5-5.0…

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SUSTAINABLE PRODUCTION OF ALLYL ALCOHOL: GAS-PHASE CONVERSION OF GLYCEROL OVER METALS PROMOTED ALUMINOSILICATE ZEOLITE CATALYSTS IN A FIXED-BED CONTINUOUS FLOW REACTOR

The present invention relates to the use of a tri-metallic promoted aluminosilicate zeolite catalyst for the direct gas-phase conversion of glycerol to allyl alcohol, as well as to a process for the production of allyl alcohol from glycerol in a fixed-bed continuous flow reactor in the presence of such heterogeneous catalysts. The method comprises conversion of glycerol to allyl alcohol in the range of temperature 250-450 °C, glycerol concentration 1-60 wt%, total gas hourly space velocity 100-2000 h-1, the weight…

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SUSTAINABLE PROCESS FOR PRODUCING MUCONIC, HEXENEDIOIC AND ADIPIC ACID (AND THEIR ESTERS) FROM ALDARIC ACIDS BY HETEROGENEOUS CATALYSIS

The Institute’s invention is a process based on selective dehydroxylation of aldaric acids derived from C6 oxidized sugars. The selective dehydroxylation is carried out in the presence of a heterogeneous carbon supported rhenium catalyst (Re/C) and a short chain primary or secondary alcohol (MeOH, EtOH, 2-PrOH,…). Under an inert (N2) atmosphere, unsaturated dimethyl ester of a C6 dicarboxylic acid is formed. If H2 is present in the gas phase, it is dissolved in MeOH and adsorbed on the catalyst surface,…

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CELL-BASED DEVICE FOR LOCAL TREATMENT WITH THERAPEUTIC PROTEINS

The Institute’s invention is a device that is comprised of a Teflon tube, permanently sealed on both ends, which contains stable cell lines. Different types of injuries demand different types of regenerative process and the device usually carries multiple types of cells, secreting multiple types of growth factors. This approach enables more control over the regeneration process and consequently better outcomes.

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SILYLATED CELLULOSE BASED INTERFACIAL PROTECTIVE LAYER ON A LITHIUM SURFACE

Lithium metal batteries are among the most promising candidates for next-generation high-density energy storage devices due to unrivalled high specific capacity and the lowest reduction potential of lithium metal anode. Estimations are that the global market will grow with a CAGR of 17% and reach the value of USD 100bn by 2025. This growth also depends on solving some of the current challenges. The usage of the lithium metal anode is obstructed by at least three issues; dendritic deposition of…

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Naložbo sofinancirata Republika Slovenija in Evropska unija iz Evropskega sklada za regionalni razvoj.